Session 150: RBMO LIVE III
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Session 150: RBMO LIVE III
Tuesday 1 April, 3pm EST / 8pm UK / 9pm CET
Moderators:
Prof. Richard Anderson and Dr. Laura Rienzi
Presenters:
Prof. Michaël Grynberg - Influence of breast cancer
prognostic factors on ovarian reserve and response to ovarian stimulation in
fertility preservation
Dr. Sarah Druckenmiller Cascante - Planned oocyte
cryopreservation: the state of the ART
Prof. Marie-Madeleine Dolmans - Fertility preservation
before sterilizing treatment: cryopreservation of both ovaries to restore
endocrine and reproductive functions
Q and A
Synopsis
The webinar, moderated by Prof. Richard Anderson and Dr. Laura Rienzi, explored current advances and challenges in fertility preservation. Prof. Michaël Grynberg began by presenting data on how breast cancer prognostic factors influenced ovarian reserve and the ovarian response to stimulation in the context of fertility preservation. His findings highlighted the complexity of preserving fertility in patients facing oncologic treatment, emphasizing individualized approaches based on the patient's cancer profile.
Dr. Sarah Druckenmiller Cascante followed with an in-depth overview of the current state of planned oocyte cryopreservation. She examined trends, outcomes, and motivations behind elective egg freezing, noting its growing acceptance and the evolving technologies that support it. Her talk also addressed patient counselling and long-term success rates.
Prof. Marie-Madeleine Dolmans concluded the session by discussing the cryopreservation of both ovaries prior to sterilizing treatments. She reviewed the dual goals of restoring endocrine and reproductive functions post-treatment, sharing insights from clinical experiences and emerging techniques that could enhance outcomes for patients undergoing gonadotoxic therapies.
The session closed with a lively Q&A, where the audience engaged the speakers with thoughtful questions, prompting further discussion on clinical decisions, patient management, and future directions in fertility preservation.
Prof. Richard Anderson
Richard Anderson is based at the Centre for Reproductive Health of the University of Edinburgh. He trained in Edinburgh, with an intercalated PhD in the MRC Brain Metabolism Unit then later started in clinical research as a WHO Research Fellow in a hormonal male contraceptive trial. He undertook Subspecialty training in Reproductive Medicine with David Baird, before spending a year in San Diego then returning to Edinburgh
Dr. Laura Rienzi
Laura Rienzi earned her Biology degree magna cum laude in 1993 from the University of Rome “La Sapienza” and completed a Post-graduate Research Fellowship at Hôpital Necker-Enfants Malades in Paris. She obtained a Master’s degree in 2009 and a Specialization in Reproductive Medicine in 2015 from the University of Padua.
Since 2016, she has been an Adjunct Professor at the University of Urbino “Carlo Bo,” becoming an Associate Professor in 2022. She has authored over 250 articles and presented at over 300 scientific meetings (scopus H-idex 64; 14.796 citations).
In 2008, she co-founded the GENERA IVF centers in Italy. In 2021, she helped create the European IVF clinic network GENERALIFE, now part of IVI-RMA Global Research Alliance, where she is on the Scientific Advisory Board.
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Prof. Michaël Grynberg
Michaël Grynberg is an internationally known, board-certified, specialist in Obstetrics & Gynecology, Reproductive Endocrinology and Infertility, Andrology. He is Professor and Director of the Department of Reproductive Medicine & Fertility Preservation in Antoine Béclère University hospital. He has been founding member of the French Society of Fertility Preservation and is currently the president elect. He is also the past coordinator of the ESHRE SIG Fertility Preservation and the Head of the Fertility Section of the French College of Obstetrician Gynecologists. He has authored 4 books, 385 scientific papers (65 book chapters, 178 peer-reviewed publications and 156 abstracts). His main research interests include: Improving the efficiency of ART, ovarian aging, fertility preservation strategies for cancer and non-medical conditions.
Dr. Sarah Druckenmiller Cascante
Sarah Druckenmiller Cascante, MD, is an Assistant Professor in the Department of Obstetrics and Gynecology at NYU Langone Fertility Center. Her research interests include oocyte cryopreservation, fertility preservation, and infertility.
Sarah Druckenmiller Cascante, MD, is an Assistant Professor in the Department of Obstetrics and Gynecology at NYU Langone Fertility Center. She earned her undergraduate degree from Columbia University and her medical degree from the NYU Grossman School of Medicine. She also completed her residency in Obstetrics & Gynecology and her fellowship in Reproductive Endocrinology at NYU. Dr. Cascante has published more than 50 scientific research manuscripts and abstracts. Her most recent clinical articles have been published in Fertility and Sterility, the Journal of Assisted Reproduction, and Reproductive Biomedicine Online. She has presented her research at national and international conferences for more than a decade, and remains actively involved in research about oocyte cryopreservation, fertility preservation, and infertility.
Prof. Marie-Madeleine Dolmans
Prof. Marie-Madeleine Dolmans earned her medical degree from the Université Catholique de Louvain in Brussels in 2000, and her PhD degree on “Cryopreservation and transplantation of human ovarian tissue” in 2006. She is gynecologist and divides her time equally between clinical and research activities. She succeeded Prof. Donnez as Head of the Gynecology Research Unit at the Université Catholique de Louvain in 2012. She is Past President of the International Society for Fertility Preservation (ISFP). Her research work focuses on ovarian transplantation, endometriosis and adenomyosis in the field of which she has published over 220 peer-reviewed articles. She is full professor, speciality editor for Fertility and Sterility and editorial board member for RBMonline, JARG, JCM.
Since 2024, she became a member of the Académie Royale Belge de Médecine (ARBM).
